10.6084/m9.figshare.11733399.v1 Watanabe N. Watanabe N. Yamamoto Y. Yamamoto Y. Sugiura T. Sugiura T. Okamura Y. Okamura Y. Ito T. Ito T. Ashida R. Ashida R. Uesaka K. Uesaka K. Supplementary Material for: The Impact of Stump Closure Techniques on Pancreatic Fistula Stratified by the Thickness of the Pancreas in Distal Pancreatectomy Karger Publishers 2020 Pancreatic fistula Distal pancreatectomy Thickness Clamp-crushing method 2020-01-27 10:13:41 Dataset https://karger.figshare.com/articles/dataset/Supplementary_Material_for_The_Impact_of_Stump_Closure_Techniques_on_Pancreatic_Fistula_Stratified_by_the_Thickness_of_the_Pancreas_in_Distal_Pancreatectomy/11733399 <b><i>Background:</i></b> The purpose of this retrospective study was to evaluate the impact of stump closure techniques on pancreatic fistula (PF) focusing on pancreatic thickness after distal pancreatectomy (DP). <b><i>Methods:</i></b> A total of 213 patients who underwent DP between 2007 and 2017 were retrospectively reviewed. The risk factors of PF were investigated. <b><i>Results:</i></b> In all patients, age ≥65 years (odds ratio [OR]: 3.60, <i>p</i> = 0.012), operation time ≥300 min (OR: 3.05, <i>p</i> = 0.013) and thickness of transected pancreas (OR: 1.37, <i>p</i> < 0.001) were identified as independent risk factors for clinically relevant PF. A receiver operating curve analysis revealed the optimum cut-off values of thickness to be 14 mm with stapler closure and 17 mm with the clamp-crushing method. There were no significant differences regarding PF between the stapler closure and clamp-crushing methods in the thin (<14 mm) and very thick pancreas (≥17 mm) groups (<i>p</i> = 0.822, <i>p</i> = 0.072). In contrast, stapler closure was the only independent risk factor for developing PF in the moderately thick (≥14, <17 mm) pancreas group (OR: 6.75 and <i>p</i> = 0.004, respectively). <b><i>Conclusion:</i></b> The clamp-crushing method was superior to stapler closure for pancreatic transection, especially in patients with moderately thick pancreas.