10.6084/m9.figshare.3437681.v1
Wenlong Rui
Wenlong
Rui
Youyu Sheng
Youyu
Sheng
Ruiming Hu
Ruiming
Hu
Ying Miao
Ying
Miao
Yumei Han
Yumei
Han
Sisi Qi
Sisi
Qi
Feng Xu
Feng
Xu
Jinhua Xu
Jinhua
Xu
Qinping Yang
Qinping
Yang
Supplementary Material for: Polymorphic CAG Repeat Numbers in the Androgen Receptor Gene of Female Pattern Hair Loss in a Han Chinese Population
Karger Publishers
2016
Female pattern hair loss
Androgen receptor
CAG repeat polymorphism
2016-06-15 14:31:13
Journal contribution
https://karger.figshare.com/articles/journal_contribution/Supplementary_Material_for_Polymorphic_CAG_Repeat_Numbers_in_the_Androgen_Receptor_Gene_of_Female_Pattern_Hair_Loss_in_a_Han_Chinese_Population/3437681
<b><i>Objective:</i></b> To investigate the association of CAG repeat numbers in the androgen receptor (AR) gene with female pattern hair loss (FPHL) in a Chinese population. <b><i>Methods:</i></b> A total of 200 Han Chinese patients with FPHL (142 Ludwig II and 58 Ludwig III cases) and 200 healthy controls were enrolled in this study. The polymorphism of CAG repeat numbers was analyzed by the fluorescent amplified fragment length polymorphism technique. <b><i>Results:</i></b> The CAG biallelic mean length was 23.73 ± 2.04 repeats in Han Chinese FPHL patients and 23.90 ± 2.13 repeats in healthy controls, without any significant difference between the two groups (p = 0.481). In addition, neither the shorter nor the longer CAG repeat numbers were significantly different between FPHL and control subjects (p = 0.726, p = 0.383). <b><i>Conclusion:</i></b> The polymorphism of CAG repeat numbers of the AR gene may not be the genetic marker of FPHL in a Chinese population.