%0 Generic
%A R.Z., Alicic
%A R.A., Short
%A C.L., Corbett
%A J.J., Neumiller
%A B.J., Gates
%A K.B., Daratha
%A C., Barbosa-Leiker
%A S., McPherson
%A N.S., Chaytor
%A B.P., Dieter
%A S.M., Setter
%A K.R., Tuttle
%D 2016
%T Supplementary Material for: Medication Intervention for Chronic Kidney Disease Patients Transitioning from Hospital to Home: Study Design and Baseline Characteristics
%U https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Medication_Intervention_for_Chronic_Kidney_Disease_Patients_Transitioning_from_Hospital_to_Home_Study_Design_and_Baseline_Characteristics/3511158
%R 10.6084/m9.figshare.3511158.v1
%2 https://karger.figshare.com/ndownloader/files/5577472
%2 https://karger.figshare.com/ndownloader/files/5577474
%K •Hospital admission
%K •Primary diagnosis
%K •Medication intervention
%K •Pharmacist
%K •Acute care utilization
%K •Chronic kidney disease management
%K •Elixhauser comorbidity measures
%X Background: The hospital readmission rate in the population with chronic kidney disease (CKD) is high and strategies to reduce this risk are urgently needed. Methods: The CKD-Medication Intervention Trial (CKD-MIT; www.clinicaltrials.gov; NCTO1459770) is a single-blind (investigators), randomized, clinical trial conducted at Providence Health Care in Spokane, Washington. Study participants are hospitalized patients with CKD stages 3-5 (not treated with kidney replacement therapy) and acute illness. The study intervention is a pharmacist-led, home-based, medication management intervention delivered within 7 days after hospital discharge. The primary outcome is a composite of hospital readmissions and visits to emergency departments and urgent care centers for 90 days following hospital discharge. Secondary outcomes are achievements of guideline-based targets for CKD risk factors and complications. Results: Enrollment began in February 2012 and ended in May 2015. At baseline, the age of participants was 69 ± 11 years (mean ± SD), 50% (77 of 155) were women, 83% (117 of 141) had hypertension and 56% (79 of 141) had diabetes. At baseline, the estimated glomerular filtration rate was 41 ± 14 ml/min/1.73 m2 and urine albumin-to-creatinine ratio was 43 mg/g (interquartile range 8-528 mg/g). The most frequent diagnosis category for the index hospital admission was cardiovascular diseases at 34% (53 of 155), but the most common single diagnosis for admission was community-acquired acute kidney injury at 10% (16 of 155). Conclusion: Participants in CKD-MIT are typical of acutely ill hospitalized patients with CKD. A medication management intervention after hospital discharge is under study to reduce post-hospitalization acute care utilization and to improve CKD management.
%I Karger Publishers