10.6084/m9.figshare.5097331.v1
Basuki T.R.
Basuki
T.R.
Triunfo S.
Triunfo
S.
Caradeux J.
Caradeux
J.
Eixarch E.
Eixarch
E.
Hansson S.
Hansson
S.
Gratacos E.
Gratacos
E.
Figueras F.
Figueras
F.
Supplementary Material for: Third-Trimester Conditional Reference Values for Longitudinal Fetal Growth Assessment
Karger Publishers
2017
Estimated fetal weight
Abdominal circumference
Gestational age
Longitudinal study
Multilevel modeling
Conditional reference values
2017-06-09 10:00:22
Journal contribution
https://karger.figshare.com/articles/journal_contribution/Supplementary_Material_for_Third-Trimester_Conditional_Reference_Values_for_Longitudinal_Fetal_Growth_Assessment/5097331
<p><b><i>Objectives:</i></b> The aim of this study was to derive
longitudinal reference values of fetal growth (estimated fetal weight
[EFW] and abdominal circumference [AC]) during the third trimester and
to develop coefficients for conditional growth assessment. <b><i>Patients and Methods:</i></b>
A prospective cohort study was conducted involving consecutive
singleton pregnancies in a low-risk population for a routine
third-trimester scan at 30<sup>+0</sup>-34<sup>+6</sup> weeks and follow-up at 37<sup>+0</sup>-38<sup>+6</sup>
weeks for an additional ultrasound. Statistical analysis was based on
multilevel modeling using MLwiN software. Unconditional centiles were
calculated from z-values at each gestational age, and conditional
centiles were calculated from z-values at a given measurement (30-34
weeks) and the expected measurement (37-38 weeks). <b><i>Results:</i></b>
At 30-34 weeks, 8 and 9.3% of the fetuses had an unconditional EFW
below the 10th and above the 90th centile, respectively. At 37-38 weeks,
these figures were 10.3 and 9.3%, respectively. Regarding the
unconditional AC, at the first scan, 8.9 and 9.6% had values below the
10th and above the 90th centile, while at the second scan 10.5 and 10.5%
had values below the 10th and above the 90th centile, respectively. The
proportion with a conditional EFW below the 10th and above the 90th
centile was 10.2 and 9.4% at the second scan, respectively. For
conditional AC, these figures were 10.7 and 10.3%, respectively. <b><i>Conclusion:</i></b> We have produced reference centiles for EFW and AC growth during the third trimester as a useful tool for quantifying growth.</p>