Supplementary Material for: Third-Trimester Conditional Reference Values for Longitudinal Fetal Growth Assessment
Basuki T.R.
Triunfo S.
Caradeux J.
Eixarch E.
Hansson S.
Gratacos E.
Figueras F.
10.6084/m9.figshare.5097331.v1
https://karger.figshare.com/articles/Supplementary_Material_for_Third-Trimester_Conditional_Reference_Values_for_Longitudinal_Fetal_Growth_Assessment/5097331
<p><b><i>Objectives:</i></b> The aim of this study was to derive
longitudinal reference values of fetal growth (estimated fetal weight
[EFW] and abdominal circumference [AC]) during the third trimester and
to develop coefficients for conditional growth assessment. <b><i>Patients and Methods:</i></b>
A prospective cohort study was conducted involving consecutive
singleton pregnancies in a low-risk population for a routine
third-trimester scan at 30<sup>+0</sup>-34<sup>+6</sup> weeks and follow-up at 37<sup>+0</sup>-38<sup>+6</sup>
weeks for an additional ultrasound. Statistical analysis was based on
multilevel modeling using MLwiN software. Unconditional centiles were
calculated from z-values at each gestational age, and conditional
centiles were calculated from z-values at a given measurement (30-34
weeks) and the expected measurement (37-38 weeks). <b><i>Results:</i></b>
At 30-34 weeks, 8 and 9.3% of the fetuses had an unconditional EFW
below the 10th and above the 90th centile, respectively. At 37-38 weeks,
these figures were 10.3 and 9.3%, respectively. Regarding the
unconditional AC, at the first scan, 8.9 and 9.6% had values below the
10th and above the 90th centile, while at the second scan 10.5 and 10.5%
had values below the 10th and above the 90th centile, respectively. The
proportion with a conditional EFW below the 10th and above the 90th
centile was 10.2 and 9.4% at the second scan, respectively. For
conditional AC, these figures were 10.7 and 10.3%, respectively. <b><i>Conclusion:</i></b> We have produced reference centiles for EFW and AC growth during the third trimester as a useful tool for quantifying growth.</p>
2017-06-09 10:00:22
Estimated fetal weight
Abdominal circumference
Gestational age
Longitudinal study
Multilevel modeling
Conditional reference values