%0 Generic
%A K., Doi
%A M., Iwagami
%A E., Yoshida
%A M.R., Marshall
%D 2017
%T Supplementary Material for: Associations of Polyethylenimine-Coated AN69ST Membrane in Continuous Renal Replacement Therapy with the Intensive Care Outcomes: Observations from a Claims Database from Japan
%U https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Associations_of_Polyethylenimine-Coated_AN69ST_Membrane_in_Continuous_Renal_Replacement_Therapy_with_the_Intensive_Care_Outcomes_Observations_from_a_Claims_Database_from_Japan/5103696
%R 10.6084/m9.figshare.5103696.v1
%2 https://karger.figshare.com/ndownloader/files/8662104
%K Continuous renal replacement therapy
%K Acute kidney injury
%K Sepsis
%K Claims database
%K Hemofilter
%X Background/Aims: Polyethylenimine-coated polyacrylonitrile (AN69ST) membrane is expected to improve the outcomes of critically ill patients treated by continuous renal replacement therapy (CRRT). Methods: Using a Japanese health insurance claim database, we identified adult patients receiving CRRT in intensive care units (ICUs) from April 2014 to October 2015. We used a multivariable logistic regression model to assess in-hospital mortality and Fine and Gray's proportional subhazards model to assess the ICU length of stay (ICU-LOS) accounting for the competing risks. Results: Of 2,469 ICU patients, 156 were treated by AN69ST membrane. Crude in-hospital mortality was 50.0% in the AN69ST group and 54.0% in the non-AN69ST group. Adjusted odds ratio (OR) of AN69ST membrane use for in-hospital mortality was 0.65 (95% CI 0.45-0.93). The use of AN69ST membrane was also independently associated with shorter ICU-LOS. Conclusion: This retrospective observational study suggested that CRRT with AN69ST membrane might be associated with better in-hospital outcomes.
%I Karger Publishers