10.6084/m9.figshare.5107276.v1
Ho D.
Ho
D.
Wang J.
Wang
J.
Homann Y.
Homann
Y.
Alphonse J.
Alphonse
J.
Beirne G.
Beirne
G.
Welsh A.W.
Welsh
A.W.
Henry A.
Henry
A.
Supplementary Material for: Use of the Myocardial Performance Index in Decreased Fetal Movement Assessment: A Case-Control Study
Karger Publishers
2017
Myocardial performance index
Tei index
Fetus
Decreased fetal movement
2017-06-14 11:23:21
Dataset
https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Use_of_the_Myocardial_Performance_Index_in_Decreased_Fetal_Movement_Assessment_A_Case-Control_Study/5107276
<p><b><i>Objectives:</i></b> To determine whether there are any fetal
cardiac function changes, as measured by the myocardial performance
index (MPI), in pregnancies complicated by decreased fetal movement
(DFM). <b><i>Methods:</i></b> We performed a prospective cross-sectional
case-control study of 50 DFM and 50 uncomplicated third-trimester
pregnancies matched within 2 gestational weeks. Routine ultrasound
growth and well-being parameters as well as MPI were measured. Average
MPI measurements and its component values were compared between the DFM
and the control group, as were demographics, other ultrasound data, and
perinatal outcomes. <b><i>Results:</i></b> Average left MPI (LMPI) and right MPI (RMPI) was similar between groups (LMPI: 0.54 ± 0.08 [DFM], 0.53 ± 0.08 [controls], <i>p</i> = 0.76; RMPI: 0.60 ± 0.12 (DFM), 0.59 ± 0.11 [controls], <i>p</i> = 0.79). However, subgroup analysis of DFM fetuses with (<i>n</i> = 20) or without (<i>n</i>
= 30) any adverse perinatal outcome demonstrated modestly higher
average RMPI and LMPI in the adverse perinatal outcome group (RMPI: 0.64
± 0.08 vs. 0.57 ± 0.13, <i>p</i> = 0.02; LMPI: 0.56 ± 0.07 vs. 0.52 ± 0.07, <i>p</i> = 0.052). <b><i>Conclusion:</i></b>
The MPI did not demonstrate clinically usable differences between the
overall DFM population and controls. However, higher LMPI and RMPI
values in the exploratory subgroup of DFM fetuses with adverse perinatal
outcomes may warrant further exploration of the MPI in DFM.</p>