10.6084/m9.figshare.5124454.v1
Savage S.
Savage
S.
Hsieh S.
Hsieh
S.
Leslie F.
Leslie
F.
Foxe D.
Foxe
D.
Piguet O.
Piguet
O.
Hodges J.R.
Hodges
J.R.
Supplementary Material for: Distinguishing Subtypes in Primary Progressive Aphasia: Application of the Sydney Language Battery
Karger Publishers
2013
Primary progressive aphasia
Cognitive assessment
Clinical diagnosis
Naming
Word repetition
Semantic knowledge
2013-02-28 00:00:00
Dataset
https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Distinguishing_Subtypes_in_Primary_Progressive_Aphasia_Application_of_the_Sydney_Language_Battery/5124454
<b><i>Background/Aims:</i></b> Primary progressive aphasia (PPA) comprises three main subtypes, varying in clinical features, patterns of brain atrophy, and underlying pathology. Differentiation of these variants is important for treatment and planning; however, simple, effective cognitive tests to aid diagnosis are lacking. This study introduces a new language battery - the SYDBAT (Sydney Language Battery) - to assist clinicians. <b><i>Methods:</i></b> Fifty-seven PPA patients and 54 age- and education-matched healthy controls were compared on naming, repetition, word comprehension, and semantic association subtests. <b><i>Results:</i></b> Significant group differences were found for all tasks, reflecting different language profiles for each group. Using discriminative function analysis, 80% of PPA cases were correctly classified from three SYDBAT scores, from which a simple diagnostic algorithm was defined. <b><i>Conclusion:</i></b> The SYDBAT is a fast and simple tool which provides a valuable adjunct to clinicians diagnosing PPA.