Supplementary Material for: Perioperative Strokes Following Surgical Correction of Mitral Valves: A Systematic Review and Meta-Analysis
Udesh R.
Natarajan P.
Jeevanantham V.
Gleason T.G.
Badhwar V.
Thirumala P.D.
10.6084/m9.figshare.5139874.v1
https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Perioperative_Strokes_Following_Surgical_Correction_of_Mitral_Valves_A_Systematic_Review_and_Meta-Analysis/5139874
<p><b><i>Objective:</i></b> The primary aim of this meta-analysis was to
quantify the impact of perioperative strokes on stroke-related
mortality after open mitral valve (MV) procedures were performed. <b><i>Methods:</i></b>
An electronic search of the PubMed, Embase, and the Web of Science
databases was performed to retrieve articles published up to December
2015, relevant to patients undergoing MV procedures. Data were extracted
from the final list of 25 studies to calculate a summary OR for 30-day
stroke-related mortality. <b><i>Results:</i></b> The stroke rate in the
total sample population was 1.62% (73/4,498). The 30-day all-cause
mortality rate was 3.51% (158/4,498). The percentage of total deaths
caused by stroke was 6.87%. The summary OR of stroke-related mortality
following MV procedures was estimated to be 7.22 (95% CI 4.13-12.63, <i>p</i>
< 0.0001). A subgroup analysis was done for studies involving
concomitant MV surgery and coronary artery bypass grafting. The summary
estimate of the subgroup showed an OR of 8.508 (95% CI 1.552-46.622, <i>p</i> = 0.0136). <b><i>Conclusion:</i></b>
Perioperative strokes following open MV procedures may be associated
with more than 7 times greater odds of 30-day stroke-related mortality.
They appear to be more commonly occurring than what is reported by
current literature, making further studies investigating possible
mechanisms and preventive measures a priority.</p>
2017-06-23 10:54:14
Mitral valve surgery
Perioperative stroke
In-hospital mortality
Morbidity