Supplementary Material for: Diagnostic Performance of Cerebroplacental Ratio Thresholds at Term for Prediction of Low Birthweight and Adverse Intrapartum and Neonatal Outcomes in a Term, Low-Risk Population
Bligh L.N.
Al Solai A.
Greer R.M.
Kumar S.
10.6084/m9.figshare.5245171.v1
https://karger.figshare.com/articles/journal_contribution/Supplementary_Material_for_Diagnostic_Performance_of_Cerebroplacental_Ratio_Thresholds_at_Term_for_Prediction_of_Low_Birthweight_and_Adverse_Intrapartum_and_Neonatal_Outcomes_in_a_Term_Low-Risk_Population/5245171
<p><b><i>Objectives:</i></b> To investigate the screening performance
and best threshold centile (5th vs. 10th) of the cerebroplacental ratio
(CPR) in low-risk, term pregnancies to predict low birthweight and
adverse intrapartum and neonatal outcomes in a term, low-risk
population. <b><i>Methods:</i></b> This was a blinded, prospective,
cross-sectional study of low-risk singleton pregnancies at term. Women
attended fortnightly from 36 weeks for CPR and estimated fetal weight
assessment. Intrapartum and neonatal outcomes were recorded. Primary
outcomes assessed were low birthweight, cesarean section for intrapartum
fetal compromise, and composite adverse neonatal outcome. <b><i>Results:</i></b>
A total of 483 women participated in the study. The CPR 10th centile
(1.48) threshold resulted in the best screening performance.
Sensitivities for low birthweight, cesarean section for intrapartum
fetal compromise, and composite adverse neonatal outcome of 41.9, 61.1,
and 38.3% were achieved for false-positive rates of 17.7, 17.7, and
15.2%, respectively. The corresponding areas under the receiver
operating characteristic curves were 0.62, 0.72, and 0.62. <b><i>Conclusion:</i></b>
The CPR 10th centile resulted in the best screening performance,
although this would be considered fair at best. The CPR 10th centile may
be useful as part of a risk stratification tool for prediction of low
birthweight and adverse intrapartum and neonatal outcomes.</p>
2017-07-26 09:23:33
Cerebroplacental ratio
Cerebroumbilical ratio
Low birthweight
Small for gestational age
Growth restriction
Cesarean section
Intrapartum fetal compromise
Fetal distress
Neonatal outcome