Supplementary Material for: Late-Onset Alopecia Areata: A Retrospective Cohort Study
Lyakhovitsky A.
Gilboa S.
Eshkol A.
Barzilai A.
Baum S.
10.6084/m9.figshare.5674558.v1
https://karger.figshare.com/articles/journal_contribution/Supplementary_Material_for_Late-Onset_Alopecia_Areata_A_Retrospective_Cohort_Study/5674558
<p><b><i>Background:</i></b> Alopecia areata is an immune-mediated
disease presenting with sudden onset of nonscarring hair loss. Onset is
more common earlier in life, and little is known regarding late-onset
alopecia areata. <b><i>Objectives:</i></b> To describe the epidemiology,
clinical patterns, disease course, and outcome of late-onset alopecia
areata in Israeli patients referred to a tertiary medical center. <b><i>Materials and Methods:</i></b>
This retrospective cohort study considered patients whose disease onset
occurred at age ≥50 years. Patients were recruited from among all
alopecia areata patients visiting a tertiary center between January 2009
and April 2015. <b><i>Results:</i></b> Of the 29 people included, 25
(86.2%) were female (female-to-male ratio, 6.2:1). There was a family
history of alopecia areata in 17.2%, thyroid disease in 31%, atopic
background in 6.9%, and 17/29 (58.6%) reported a significant stressful
event. The most common disease pattern was patchy, and disease was mild
in the majority of participants. Complete hair regrowth was observed in
82.8% of participants, and 37.9% relapsed. <b><i>Conclusion:</i></b>
Late-onset alopecia areata is characterized by marked female
predominance, less extensive disease, and a high incidence of complete
hair regrowth.</p>
2017-12-06 09:44:43
Age of onset
Alopecia
Alopecia areata
Hair disorders
Late onset