10.6084/m9.figshare.5675065.v1
Heidari Tajabadi F.
Heidari Tajabadi
F.
Medrano-Soto A.
Medrano-Soto
A.
Ahmadzadeh M.
Ahmadzadeh
M.
Salehi Jouzani G.
Salehi Jouzani
G.
Saier Jr. M.H.
Saier Jr.
M.H.
Supplementary Material for: Comparative Analyses of Transport Proteins Encoded within the Genomes of Bdellovibrio bacteriovorus HD100 and Bdellovibrio exovorus JSS
Karger Publishers
2017
Predator
Bdellovibrio bacteriovorus
Bdellovibrio exovorus
Comparative genomics
Transport proteins
2017-12-06 15:08:10
Journal contribution
https://karger.figshare.com/articles/journal_contribution/Supplementary_Material_for_Comparative_Analyses_of_Transport_Proteins_Encoded_within_the_Genomes_of_Bdellovibrio_bacteriovorus_HD100_and_Bdellovibrio_exovorus_JSS/5675065
<p><i>Bdellovibrio</i>, δ-proteobacteria, including <i>B. bacteriovorus</i> (Bba) and <i>B. exovorus</i>
(Bex), are obligate predators of other Gram-negative bacteria. While
Bba grows in the periplasm of the prey cell, Bex grows externally. We
have analyzed and compared the transport proteins of these 2 organisms
based on the current contents of the Transporter Classification Database
(TCDB; www.tcdb.org). Bba has 103 transporters more than Bex, 50% more
secondary carriers, and 3 times as many MFS carriers. Bba has far more
metabolite transporters than Bex as expected from its larger genome, but
there are 2 times more carbohydrate uptake and drug efflux systems, and
3 times more lipid transporters. Bba also has polyamine and carboxylate
transporters lacking in Bex. Bba has more than twice as many members of
the Mot-Exb family of energizers, but both may have energizers for
gliding motility. They use entirely different types of systems for iron
acquisition. Both contain unexpectedly large numbers of pseudogenes and
incomplete systems, suggesting that they are undergoing genome size
reduction. Interestingly, all 5 outer-membrane receptors in Bba are
lacking in Bex. The 2 organisms have similar numbers and types of
peptide and amino acid uptake systems as well as protein and
carbohydrate secretion systems. The differences observed correlate with
and may account, in part, for the different lifestyles of these 2
bacterial predators.</p>