10.6084/m9.figshare.5678866.v1
Shirai H.
Shirai
H.
Kaido T.
Kaido
T.
Hamaguchi Y.
Hamaguchi
Y.
Kobayashi A.
Kobayashi
A.
Okumura S.
Okumura
S.
Yao S.
Yao
S.
Yagi S.
Yagi
S.
Kamo N.
Kamo
N.
Taura K.
Taura
K.
Okajima H.
Okajima
H.
Uemoto S.
Uemoto
S.
Supplementary Material for: Preoperative Low Muscle Mass and Low Muscle Quality Negatively Impact on Pulmonary Function in Patients Undergoing Hepatectomy for Hepatocellular Carcinoma
Karger Publishers
2017
Sarcopenia
Cardiac function
Pulmonary function
Hepatocellular carcinoma
Psoas muscle index
Intramuscular adipose tissue content
2017-12-07 13:39:07
Presentation
https://karger.figshare.com/articles/presentation/Supplementary_Material_for_Preoperative_Low_Muscle_Mass_and_Low_Muscle_Quality_Negatively_Impact_on_Pulmonary_Function_in_Patients_Undergoing_Hepatectomy_for_Hepatocellular_Carcinoma/5678866
<p><b><i>Background:</i></b> Sarcopenia is a prognostic factor for
mortality in digestive surgery. However, the correlation between
preoperative cardiopulmonary function and sarcopenia in patients
undergoing hepatectomy for hepatocellular carcinoma (HCC) remains
unclear. <b><i>Methods:</i></b> The present study investigated the
impact of preoperative sarcopenia on cardiopulmonary function in 402
patients who underwent first hepatectomy for HCC between April 2005 and
April 2015. The quantity and quality of skeletal muscle were evaluated
using psoas muscle index (PMI) and intramuscular adipose tissue content
(IMAC), respectively, as determined from preoperative computed
tomography imaging. Correlations between preoperative cardiopulmonary
function and sarcopenic factors (PMI and IMAC) were evaluated. <b><i>Results:</i></b>
No significant correlations were found between left ventricular
ejection fraction and the two sarcopenic factors. On the other hand,
preoperative vital capacity (VC) and forced expiratory volume in 1 s
(FEV<sub>1</sub>) correlated significantly with PMI (<i>p</i> < 0.001 each) in males and with IMAC (<i>p</i> < 0.001 each) in females. Moreover, VC and FEV<sub>1</sub> in the preoperative low PMI (<i>p</i> < 0.001 each) and high IMAC (<i>p</i> = 0.002 and <i>p</i> < 0.001, respectively) groups were significantly lower than in the normal group in males. In females, VC and FEV<sub>1</sub> were significantly lower in the preoperative high IMAC group than in the normal group (<i>p</i> < 0.001 each). <b><i>Conclusion:</i></b>
Preoperative low muscle mass in males and low muscle quality in males
and females were significantly associated with pulmonary dysfunction.</p>