Supplementary Material for: Onset to Reperfusion Time Was Not Important in Mechanical Thrombectomy for Elderly Patients: A Retrospective Multicenter Study in Tama Area, Tokyo Koizumi S. Ota T. Shigeta K. Amano T. Ueda M. Matsumaru Y. Shiokawa Y. Hirano T. 10.6084/m9.figshare.7053506.v1 https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Onset_to_Reperfusion_Time_Was_Not_Important_in_Mechanical_Thrombectomy_for_Elderly_Patients_A_Retrospective_Multicenter_Study_in_Tama_Area_Tokyo/7053506 <b><i>Background:</i></b> Mechanical thrombectomy (MT) has become the standard of care for acute ischemic stroke with large vessel occlusion; however, evidence remains insufficient for MT for elderly patients, especially with respect to factors affecting their outcomes. <b><i>Methods:</i></b> This study was a retrospective analysis of a multicenter registry of MT, called Tama Registry of Acute Endovascular Thrombectomy. Patients were divided by their age into 2 groups: Nonelderly (NE; < 80) and elderly (E; ≥80). Factors related to a good outcome (modified Rankin scale score ≤2) were examined in each group. Onset to reperfusion time (OTR) was stratified into 4 categories: category 1, 0 – ≤180 min; category 2, > 180 – ≤360 min; category 3, > 360 min or onset time not identified; and category 4, effective recanalization not achievable. <b><i>Results:</i></b> 143 NE patients and 78 E patients were included in this study. The E group had less chance of achieving a good outcome (NE group 51%, E group 35%; <i>p</i> = 0.024). In the NE group, lower OTR category was an independent prognostic factor for good outcome (<i>p</i> = 0.037, OR = 1.09). However, in the E group, OTR category was not a significant predictor on multivariate analysis. Instead, effective recanalization (<i>p</i> = 0.0081, OR 1.40) and lower National Institute of Health Stroke Scale score at presentation (<i>p</i> = 0.0032, OR 1.02) were the independent predictors. <b><i>Conclusions:</i></b> In MT for elderly patients, effective recanalization improved the patients’ outcome but OTR affected less. Further studies are warranted to establish the appropriate patient selection and treatment strategies. 2018-09-06 09:41:14 Acute ischemic stroke Geriatrics Mechanical thrombectomy