Supplementary Material for: Epidemiology of Multiple Sclerosis in Austria

S., Salhofer-Polanyi; H., Cetin; F., Leutmezer; A., Baumgartner; S., Blechinger; A., Dal-Bianco; P., Altmann; B., Bajer-Kornek; P., Rommer; M., Guger; D., Leitner-Bohn; B., Reichardt; F., Alasti; W., Temsch; T., Stamm

doi:10.6084/m9.figshare.5324977.v1

479696_sm1.PDF (47.46 kB)

Supplementary Material for: Epidemiology of Multiple Sclerosis in Austria

journal contribution

posted on 2017-08-18, 09:45 authored by Salhofer-Polanyi S., Cetin H., Leutmezer F., Baumgartner A., Blechinger S., Dal-Bianco A., Altmann P., Bajer-Kornek B., Rommer P., Guger M., Leitner-Bohn D., Reichardt B., Alasti F., Temsch W., Stamm T.

Background: To assess the incidence rate and prevalence ratio of multiple sclerosis (MS) in Austria. Methods: Hospital discharge diagnosis and MS-specific immunomodulatory treatment prescriptions from public health insurances, covering 98% of Austrian citizens with health insurance were used to extrapolate incidence and prevalence numbers based on the capture-recapture method. Results: A total of 1,392,629 medication prescriptions and 40,956 hospitalizations were extracted from 2 data sources, leading to a total of 13,205 patients. The incidence rate and prevalence ratio of MS in Austria based on the capture-recapture method were 19.5/100,000 person-years (95% CI 14.3-24.7) and 158.9/100,000 (95% CI 141.2-175.9), respectively. Female to male ratio was 1.6 for incidence and 2.2 for prevalence. Conclusions: Incidence rates and prevalence ratios of MS in our study are within the upper range of comparable studies across many European countries as well as the United States.