Supplementary Material for: Low Density Lipoprotein Cholesterol and the Outcome of Acute Ischemic Stroke: Results of a Large Hospital-Based Study

Version 2 2016-10-06, 07:14

Version 1 2016-10-06, 06:27

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posted on 2016-10-06, 07:14 authored by Xing Y., An Z., Yu N., Zhao W., Ning X., Wang J.

Studies show inconsistent associations between low-density lipoprotein cholesterol (LDL-C) and stroke outcome. We assessed these associations among patients with first-ever acute ischemic stroke (AIS) in China. Patients with first-ever AIS were categorized into 3 groups: normal LDL, marginally elevated LDL and high LDL - according to the LDL-C values on admission. The outcome measures that were investigated in each group included mortality, dependence and recurrence of vascular events. Patients with high LDL-C had higher mortality rates than did those with normal LDL-C at both 12 and 36 months, but this difference disappeared after adjustment for covariates. There was no difference between groups in mortality at 3 months and dependency or recurrence at 3, 12 or 36 months. LDL-C level was associated with long-term mortality after stroke, but was not an independent prognostic factor.