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Supplementary Material for: Berücksichtigung von Wechsel- und Nebenwirkungen bei pflanzlichen Arzneimitteln in deutschen S3-Leitlinien der AWMF

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posted on 24.06.2016, 10:51 by Klose P., Kraft K., Lauche R, Cramer H., Dobos G., Langhorst J.
Herbal remedies have a long history in the medical care of
the German-speaking regions but they are rarely taken into
account in the development of medical guidelines. In a prestudy,
our working group analyzed as to how far herbal
remedies were taken into consideration in the current interdisciplinary
evidence- and consensus-based S3 medical
guidelines established by the Association of the Scientific
Medical Societies (AWMF) in Germany. The aim of this
study was to analyze to what extent possible side effects
and interactions of herbal remedies are mentioned in the S3
medical guidelines. In January 2015, 134 S3 guidelines were
counted and analyzed. 27.6% (n = 37) of them show 194
statements summarized under the term ‘phytotherapy’. References
to side effects and interactions can be found in
28.4% of the statements (n = 55); 13.9% (n = 27) of these
references are backed by the literature. 14 of the statements
deal with nutritional supplements, 11 are statements about
phytotherapy in general, and 7 summarize at least 2 medical
plants in 1 statement. Hence, only 23 statements pay attention
to side effects and interactions of individual medical
plants; 14 of these are backed by the literature. These results
do not correspond to the standards required by the
AWMF, which is due to imprecise terms as well as to the
insufficiently systematic approach in the search for scientific
evidence for the safety of medical plants. Here, the Association
for Phytotherapy may achieve an important contribution
to quality improvement.