Karger Publishers
Browse
Supplementary material-CARE_checklist_Transgender.pdf (777.1 kB)

Supplementary Material for: Complexities in Adjuvant Endocrine Therapy for Breast Cancer in Female-to-Male Transgender Patients

Download (777.1 kB)
dataset
posted on 2024-02-07, 15:33 authored by Sato S., Imada S., Hayami R., Arai K., Kosugi R., Tsuneizumi M., Matsunuma R.
Introduction: Managing breast cancer in female-to-male (FtM) transgender patients is complicated and challenging. Androgens play a crucial role in the development of secondary sexual identity in FtM transgender patients, but their effectiveness in breast cancer remains unclear. Furthermore, the considerations for adjuvant endocrine therapy in this population are highly intricate and warrant thorough discussion. Case Presentation: We describe the case of a 44-year-old FtM transgender diagnosed with breast cancer 3 years after initiating androgen receptor agonist therapy as part of his gender identity transition. After mastectomy, adjuvant endocrine therapy was initiated, consisting of a combination of an aromatase inhibitor and a gonadotropin-releasing hormone agonist, along with a cross-sex hormone. Conclusion: Estradiol levels were significantly reduced, and male-typical levels of sex hormones were attained.

History

Usage metrics

    Case Reports in Oncology

    Categories

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC