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Supplementary Material for: Feasibility and Safety of a Coaxial Dual-Wavelength Optical Coherence Tomography Apparatus

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posted on 04.08.2020, 09:51 by Cedro L., Hasler P.W., Meier C., Povazay B., Burri C., Mooser M., Kaiser P., Rothenbuehler S.P., Müller P.L., Zarranz-Ventura J., Egan C., Tufail A., Scholl H.P.N., Maloca P.M.
Purpose: To evaluate the feasibility and safety of a coaxial dual-wavelength optical coherence tomography (OCT) device (marked as Hydra-OCT). Methods: Healthy participants without ocular pathology underwent retinal imaging using the Hydra-OCT allowing for simultaneous measurement of retinal scanning of 840 and 1,072 nm wavelength. Before and after measurement, best-corrected visual acuity and patients’ comfort were assessed. Representative OCT images from both wavelengths were compared by 5 independent graders using a subjective grading scheme. Results: A total of 30 eyes of 30 participants (8 females and 22 males) with a mean age of 26.5 years (range from 19 to 55 years) were included. Dual-wavelength image acquisition was made possible in each subject. The participant’s effort and comfort assessment using the Hydra-OCT imaging revealed an equivalent value as compared to the commercially available OCT machine. No adverse events were reported, and visual acuity was not altered by the Hydra-OCT. Imaging between the systems was comparable. Conclusions: This study provides evidence for the feasibility and safety of a coaxial dual-wavelength OCT imaging method under real-life conditions. The novel Hydra-OCT imaging device may offer additional insights into the pathology of retinal and choroidal diseases.