Supplementary Material for: Fovea sparing branch retinal artery occlusions imaged with optical coherence tomography angiography: two case reports

Introduction: Central retinal artery occlusions (CRAOs) and branch retinal artery occlusions (BRAOs) are ophthalmic emergencies that require workups for systemic risk factors. In the acute setting, BRAOs present with retinal whitening in a sectoral pattern on exam as well as hyperreflectivity and thickening of the inner retinal layers on optical coherence tomography (OCT). In the subacute to chronic phase, the retinal whitening dissipates, which may confound the diagnosis of remote arterial occlusions if there is no clearly visible plaque. Case Presentations: A 66-year-old male presented with 20/25 visual acuity (VA) and an inferior visual field defect in the right eye, and a 69-year-old male presented with 20/60 VA and a superior visual field defect in the left eye. Exams of both patients showed ischemic retinal whitening with visible Hollenhorst plaques in the affected eyes. Optical coherence tomography (OCT) demonstrated inner retinal edema. At follow-up, wide-field OCT-angiography (OCTA) showed persistent capillary dropout following the same initial vascular distribution but sparing the fovea and papillomacular bundle. VAs at the most recent follow-up visits were 20/30 and 20/20, respectively. Conclusion: These cases demonstrate the utility of wide-field OCTA in characterizing areas of capillary nonperfusion that can persist for years after the initial ischemic event. Additionally, patients with macula-involving BRAOs can have good visual acuity outcomes if the fovea is spared.