Supplementary Material for: Public attitudes towards the DEA’s proposal to reschedule marijuana: a cross-sectional mixed methods analysis

Introduction: On May 21, 2024, the Drug Enforcement Agency (DEA) published a proposed rule to reschedule marijuana from schedule I to III under the Controlled Substance Act (CSA), followed by a 60-day open comment period. The purpose of this study is to analyze the public attitudes regarding the proposed rule and identify trends based on time of comment submission and recurring arguments throughout the comments. Methods: This was an observational, cross-sectional, mixed-methods study. Comments from the proposal were stratified according to the submission date as early (5-21-6/11), mid (6/12-7/2), and late (7/3-7/22) respondents. Investigators were assigned an equal number of comments to code as in favor of, against, or no clear position on rescheduling. Comments were further coded based on type of comment (form letters, personal anecdotes), rationale for comment (racism, decriminalization, safety, and economic factors), and whether descheduling was favored. Chi-square tests were used to analyze categorical data. A random sample of comments were selected to assure a 5% margin of error. Results: More than 42,000 comments were submitted. Of these, 380 comments were selected and coded, with 42% (n=158) in support of rescheduling, 55% (n=211) against rescheduling, and 2.9% (n=11) with no clear position. Of all comments coded, 71% wanted to go further and were in support of descheduling. The early responses consisted of a majority in favor of rescheduling, while the mid and late responses consisted of more comments against rescheduling [X2 (2, N = 369) = 35.8, p<0.00001]. Of the comments against rescheduling, a large majority supported descheduling [X2 (2, N = 265 = 32.0, p<0.0001)]. As for comment structure, 69% (n=263) of all comments coded were form letters, while 8.4% (n=32) were personal anecdotes. Conclusion: The number of comments in support of rescheduling decreased with time, only dominating the early respondent wave. Despite a larger number of negative attitudes towards the DEA’s proposed rule of rescheduling marijuana from schedule I to III, a majority of comments supported taking a step further to deschedule marijuana all together.