Supplementary Material for: Sickle cell crisis induced painless bilateral orbital bone infarction: A case report

Sickle cell disease is associated with painful vaso-occlusive crises, bone infarction, avascular necrosis, and osteomyelitis. Sickle cell orbitopathy is a rare manifestation with signs similar to periorbital cellulitis and has subtle radiologic features. We report a case of a five-year-old girl with sickle cell who presented with bilateral orbital infarctions and subperiosteal hematomas, notably without periorbital pain, and was treated with antibiotics and steroids. Physicians should be aware of this rare manifestation, especially in the pediatric population, as it can affect subsequent management.