Supplementary Material for: The Hole Story: Spontaneous Closure After Reopening

Introduction We report a case of spontaneous closure after early reopening of a previously successfully treated macular hole (MH). Case Presentation A 73-year-old patient presented with visual acuity of 20/100 and complained of defective vision. Examination and investigations confirmed a full-thickness MH. Surgical intervention led to complete closure of the hole on OCT within 5 days. However, the patient reported recurrence of symptoms 2 weeks later, and reopening of the hole was diagnosed. Re-surgery was advised, but surprisingly, the hole spontaneously closed by the seventh week and remained closed at the last follow-up (6 months post-surgery), with visual acuity improving to 20/50. Conclusions Reopening of a MH can occur months or years after successful treatment, and the underlying reasons remain unclear. While reoperation is often indicated, spontaneous healing, although rare, is possible. This case highlights the potential for spontaneous closure of a reopened macular hole, suggesting that a wait-and-watch approach may be worthwhile before deciding on further surgery.